I hope and believe the Lions and Duron Harmon go their separate ways. Harmon wasn't reliable enough as a tackler in the 2020 season. His ball skills weren't at the level he displayed with New England. Harmon doesn't seem to have enough versatility.
Duron Harmon likely will want to go to a team that will use him mainly as a FS, with many similarities to Matt Patricia's Defense. Going to a team that would give Harmon a much better chance for him to get his 4th Super Bowl winning ring probably is something he considers important.